Journal of Siberian Federal University. Biology / Obtaining and Investigation of Polymer Compositions Based on Poly-3-Hydroxybutyrate

Full text (.pdf)
Issue
Journal of Siberian Federal University. Biology. 2014 7 (2)
Authors
Boyandin, Anatoly N.; Nikolaeva, Elena D.; Shabanov, Alexander V.; Vasiliev, Alexander D.
Contact information
Boyandin, Anatoly N.:Institute of Biophysics SB RAS 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia; Siberian Federal University;E-mail: ; Nikolaeva, Elena D.:Institute of Biophysics SB RAS 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia; Shabanov, Alexander V.:L.V. Kirensky Institute of Physics SB RAS 50/38 Akademgorodok, Krasnoyarsk, 660036, Russia; Vasiliev, Alexander D.:L.V. Kirensky Institute of Physics SB RAS 50/38 Akademgorodok, Krasnoyarsk, 660036, Russia
Keywords
biopolymers; polyhydroxybutyrate; polycaprolactone; polylactide; polyethylene oxide; starch; biocompatibility
Abstract

The morphology, surface properties and biocompatibility of mixtures of poly-3-hydroxybutyrate with poly-ε-caprolactone, poly-DL-lactide, polyethylene glycol and starch were studied. Differences in the film surface microstructure were revealed using electron microscopy: composites of P(3HB) with PEG and PCL had a more coarse-pored surface compared to the pure P(3HB). Addition of PEG led to a significant increase in surface hydrophilicity. In the culture of mouse NIH 3T3 fibroblasts the following effects were observed: the absence of cytotoxic effect, the presence of cell adhesion and proliferation. Thus, the biocompatibility of the studied composites and their suitability for production of polymer products for cellular technologies was shown

Pages
174-185
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/13404

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