Journal of Siberian Federal University. Chemistry / Enterosorbents from Abies Bark and their Therapeutic and Preventive Properties in Experimental Escherichiosis of Animals

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Issue
Journal of Siberian Federal University. Chemistry. 2020 13 (1)
Authors
Kuznetsova, Svetlana A.; Skvortsova, Galina P.; Moroz, Anastasya A.; Schislenko, Svetlana A.; Korolkova, Irina V.; Chesnokov, Nikolai V.; Kuznetsov, Boris N.
Contact information
Kuznetsova, Svetlana A.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” Krasnoyarsk, Russian Federation; ; Skvortsova, Galina P.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” Krasnoyarsk, Russian Federation; Moroz, Anastasya A.: Krasnoyarsk State Agrarian University Krasnoyarsk, Russian Federation; Schislenko, Svetlana A.: Krasnoyarsk State Agrarian University Krasnoyarsk, Russian Federation; Korolkova, Irina V.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” Krasnoyarsk, Russian Federation; Chesnokov, Nikolai V.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” Krasnoyarsk, Russian Federation; Kuznetsov, Boris N.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” Krasnoyarsk, Russian Federation; Siberian Federal University Krasnoyarsk, Russian Federation
Keywords
abies bark; enterosorbent; sorption; methylene blue; gelatin; gastrointestinal infections
Abstract

Methods have been developed for the preparation of enterosorbents by treating crushed abies bark with the 1.5% aqueous of NaOH solution or by extraction with hexane. It was found that all obtained enterosorbents have good sorption properties with respect to gelatin and methylene blue. The highest sorption activity for methylene blue was shown by a sample, obtained by extraction of abies bark with hexane (97.0 mg/g), and for gelatin sorption activity – a sample, obtained by treatment of abies bark with alkali (225.0 mg/g). It was found that the enterosorbent, obtained by treatment of abies bark with alkali solution both at a dose of 0.15 g per kg of animal weight (g/kg) and at a dose of 0.20 g/kg and the enterosorbent, obtained by extraction of abies bark with hexane at a dose of 0.20 g/kg, have the highest efficiency for the treatment and prevention of acute experimental Escherichiosis. From the considered methods of obtaining enterosorbents from abies bark for the treatment and prevention of gastrointestinal infections of animals, it is recomended to use a method based on treatment of abies bark with alkalai solution and apply the drug in a dose of 0.15 g/kg

Pages
122-132
DOI
10.17516/1998-2836-0158
Paper at repository of SibFU
http://elib.sfu-kras.ru/handle/2311/135089