- Supplementary material
- Application 1 (.pdf, 710 KB)
- Issue
- Journal of Siberian Federal University. Chemistry. 2021 14 (3)
- Authors
- Novikova, Galina V.; Tsyplenkova, Darya I.; Kuzubov, Alexander A.; Kolenchukova, Oksana A.; Samoilo, Alexander S.; Vorobyev, Sergey A.
- Contact information
- Novikova, Galina V.: School of Non-Ferrous Metals and Materials Science, Siberian Federal University Krasnoyarsk, Russian Federation; ; Tsyplenkova, Darya I.: School of Non-Ferrous Metals and Materials Science, Siberian Federal University Krasnoyarsk, Russian Federation; Kuzubov, Alexander A.: School of Non-Ferrous Metals and Materials Science, Siberian Federal University Krasnoyarsk, Russian Federation; L.V. Kirensky Institute of Physics SB RAS FRC «Krasnoyarsk Science Center SB RAS» Krasnoyarsk, Russian Federation; Kolenchukova, Oksana A.: Scientific Research Institute of Medical Problems of the North FRC «Krasnoyarsk Scientific Center of the SB RAS» Krasnoyarsk, Russian Federation; Samoilo, Alexander S.: School of Non-Ferrous Metals and Materials Science, Siberian Federal University Krasnoyarsk, Russian Federation; Vorobyev, Sergey A.: Institute of Chemistry and Chemical Technology SB RAS, FRC «Krasnoyarsk Scientific Center of the SB RAS» Krasnoyarsk, Russian Federation
- Keywords
- ceftriaxone; calcium; DFT; IR spectroscopy; luminescence properties; antibacterial screening
- Abstract
The calcium complex of ceftriaxone was synthesized and characterized by elemental, atomic-emission analysis, TGA, IR spectroscopy and density functional theory calculations. The luminescence and antibacterial properties of the ceftriaxone disodium and calcium complex were investigated. Ca(II) complex was obtained in a crystalline form, cell parameters of the compound were determined. Ceftriaxone was coordinated to the calcium ion by the oxygen of the triazine cycle in the 6th position, the nitrogen of the amine group of the thiazole ring, and the oxygens of the lactam carbonyl and carboxylate groups. The complex of Ca(II) with ceftriaxone was screened for antibacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, and the results were compared with the activity of ceftriaxone disodium salt
- Pages
- 290–301
- DOI
- 10.17516/1998-2836-0238
- Paper at repository of SibFU
- https://elib.sfu-kras.ru/handle/2311/144180
Journal of Siberian Federal University. Chemistry / Complex of Ca(II) with Ceftriaxone: Synthesis, Structure, Spectral and Antibacterial Properties
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