- Issue
- Journal of Siberian Federal University. Biology. 2021 14 (4)
- Authors
- .Vinnik, Yuri S.; Solovyeva, Natalia S.; Zuev, Andrey P.; Polezhaev, Leonid A.
- Contact information
- Vinnik, Yuri S.: Prof. V. F. Voino-Yasenetsky Krasnoyarsk State Medical University Krasnoyarsk, Russian Federation; ORCID: 0000-0002-8995-2862; Solovyeva, Natalia S.: Voino-Yasenetsky Krasnoyarsk State Medical University Krasnoyarsk, Russian Federation; Zuev, Andrey P.: Voino-Yasenetsky Krasnoyarsk State Medical University Krasnoyarsk, Russian Federation; Polezhaev, Leonid A.: Voino-Yasenetsky Krasnoyarsk State Medical University Krasnoyarsk, Russian Federation
- Keywords
- wound coating; trophic ulcer; cellulose; nanosilver
- Abstract
Chronic venous insufficiency is a common condition that affects people of different ages. Trophic ulcers are a complication of venous insufficiency which is difficult to treat. Therefore, development of new, combined methods of treatment using coatings that have both antibacterial and wound healing properties is a topical issue. The article presents a comparative analysis of clinical trials of wound coatings based on bacterial cellulose (experimental group 1), cellulose loaded with silver (experimental group 2), and «Hydrocall» (control group) in treatment of trophic ulcers in patients with chronic venous insufficiency. Application of all types of wound coatings demonstrated a positive dynamics of healing. Complete epithelialization was observed in experimental group 2 by the 42nd day, whereas in patients of the control group, epithelialisation was not complete by the 45th day. Thus, application of wound coatings based on cellulose loaded with silver shortened the epithelialisation process and trophic ulcers healing, which justifies to their efficiency and practicality
- Pages
- 526–532
- DOI
- 10.17516/1997-1389-0369
- Paper at repository of SibFU
- https://elib.sfu-kras.ru/handle/2311/145139
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).