Journal of Siberian Federal University. Chemistry / Preparation of a New Drug Based on Cis-Dichlorodiamminplatin(II), Arabinogalactan and Aptamer AS‑42 and Study of its Biological Activity

Full text (.pdf)
Issue
Journal of Siberian Federal University. Chemistry. 2022 15 (1)
Authors
Starkov, Alexander K.; Kirik, Sergey D.; Zamay, Tatyana N.; Kozuchovskaya, Galina A.; Rubaylo, Anatoliy I.
Contact information
Starkov, Alexander K.: Institute of Chemistry and Chemical Technology SB RAS FRC «Krasnoyarsk Science Center SB RAS» Krasnoyarsk, Russian Federation; ; Kirik, Sergey D.: Institute of Chemistry and Chemical Technology SB RAS FRC «Krasnoyarsk Science Center SB RAS» Krasnoyarsk, Russian Federation; Siberian Federal University Krasnoyarsk, Russian Federation; Zamay, Tatyana N.: Krasnoyarsk State Medical University named after Prof. V. F. Voino-Yasenetsky Krasnoyarsk, Russian Federation; Kozuchovskaya, Galina A.: Institute of Chemistry and Chemical Technology SB RAS FRC «Krasnoyarsk Science Center SB RAS» Krasnoyarsk, Russian Federation; Rubaylo, Anatoly I.: Institute of Chemistry and Chemical Technology SB RAS Krasnoyarsk, Russian Federation; Siberian Federal University Krasnoyarsk, Russian Federation
Keywords
platinum complex compound; synthesis; physico-chemical properties; arabinogalactan; aptamers
Abstract

A new drug based on a complex of cis-dichlorodiamminplatin(II) with arabinogalactan and aptamer AS‑42 was obtained. The drug is characterized by the methods of XRD, thermogravimetry. IR spectroscopy. Its biological activity has been studied

Pages
81–89
DOI
10.17516/1998-2836-0273
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/145232