Siberian Federal University 
- Issue
- Journal of Siberian Federal University. Chemistry. 2022 15 (2)
- Authors
- Tsokova, Tatyana N.; Kotlova, Lyudmila I.
- Contact information
- Tsokova, Tatyana N.: Tyumen State Medical University Tyumen, Russian Federation; ; Kotlova, Lyudmila I.: Tyumen State Medical University Tyumen, Russian Federation
- Keywords
- citramone; acetylsalicylic acid; paracetamol; caffeine; UV absorption spectra; method of differentiation of absorption spectra; polynomial differentiation
- Abstract
The effectiveness of using quantitative analysis of the components of Citramon – P tablets from different manufacturers by differentiating UV absorption spectra by Chebyshev polynomials has been studied. The criteria for its successful application have been established. A method of dilution of Citramon tablets has been developed, solvents have been selected for qualitative and quantitative analysis of samples. A linear relationship between the coefficients of optimal polynomials and the concentration for each component of the mixture at the points of maximum absorption is revealed. The equations of calibration graphs are found, the conditions of their use are discussed
- Pages
- 206–213
- DOI
- 10.17516/1998-2836-0285
- Paper at repository of SibFU
- https://elib.sfu-kras.ru/handle/2311/145625
Journal of Siberian Federal University. Chemistry / Quantitative Determination of the Concentration of Medicinal Substances in Citramon Tablets by the Method of Differentiation of Absorption Spectra by Chebyshev Polynomials
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