Journal of Siberian Federal University. Chemistry: The Reaction Product of the Complex Cis-Dichlorodiamminplatinum(II) with Matrix Carrier Arabinogalactan and its Properties

Journal of Siberian Federal University. Chemistry / The Reaction Product of the Complex Cis-Dichlorodiamminplatinum(II) with Matrix Carrier Arabinogalactan and its Properties

Issue: Journal of Siberian Federal University. Chemistry. 2015 8 (2)
Authors: Starkov, Alexander K.; Kozuchovskaya, Galina A.; Pavlenko, Nina I.
Contact information: Starkov, Alexander K.:Institute of Chemistry and Chemical Technology SB RAS 42 K. Marx Str., Krasnoyarsk, 660049, Russia; Kozuchovskaya, Galina A.:Institute of Chemistry and Chemical Technology SB RAS 42 K. Marx Str., Krasnoyarsk, 660049, Russia; Pavlenko, Nina I.:Institute of Chemistry and Chemical Technology SB RAS 42 K. Marx Str., Krasnoyarsk, 660049, Russia;E-mail:
Keywords: complex compounds of platinum; synthesis; physicochemical properties; amines; arabinogalactan
Abstract: The obtained product of reaction of the complex cis-dichlorodiaminplatinum(II) with matrix carrior arabinogalactan was characterized by XRD, IR-spectroscopy and thermogravimetry. The composition and structure of this product was installed. It has been shown that cis-dichlorodiaminplatinum(II) associated with arabinogalactan through communications –C-O-C- amino hydrogen of the original complex. The preliminary study of a synthesized product on the biological activity showed that the product inhibits tumor growth and it does not have toxic effects on the body. This product is more soluble and exibits a greater activity as compared to cis-dichlorodiaminplatinum(II)
Pages: 269-276
Paper at repository of SibFU: https://elib.sfu-kras.ru/handle/2311/19766