Journal of Siberian Federal University. Biology / Wound Dressings Made of Biodegradable Natural Polymers Polyhydroxyalkanoates (PHAs): Production and Properties

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Issue
Journal of Siberian Federal University. Biology. 2016 9 (1)
Authors
Borovkova, Natalia V.; Evseev, Anatoly K.; Andreev, Yury V.; Goncharovb, Dmitry B.; Shishatskaya, Ekaterina I.
Contact information
Borovkova, Natalia V.:N.V. Sklifosovsky Institute of Emergency Care 3 Bolshaya Suharevskaya sq., Moscow, 129090, Russia; Evseev, Anatoly K.:N.V. Sklifosovsky Institute of Emergency Care 3 Bolshaya Suharevskaya sq., Moscow, 129090, Russia; Andreev, Yury V.:N.V. Sklifosovsky Institute of Emergency Care 3 Bolshaya Suharevskaya sq., Moscow, 129090, Russia; Goncharovb, Dmitry B.:Institute of Biophysics of SB RAS 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia; Shishatskaya, Ekaterina I.:Institute of Biophysics of SB RAS 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia; E-mail:
Keywords
polyhydroxyalkanoates; wound dressing; electrospinning; skin regeneration
Abstract

Increasing number of industrial and household injuries and burns lead to the necessity of research and development of new materials and resources for damaged skin regeneration. In this study results of experimental investigation of wound dressing made of natural degradable polyesters polyhydroxyalkanoates (PHAs) using electrospinning are presented. Studies on laboratory animals with model skin burns showed that the developed PHA membranes provide regeneration of the skin after 7 days and it is comparable with the control collagen dressings used in clinical practice. Developed nonwoven membranes may be used as the equivalent of collagen dressings in the treatment of II degree burns

Pages
88-97
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/20184

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