Journal of Siberian Federal University. Biology / Reconstruction of Model Defects of the Orbit of Laboratory Animals with Use of Resorbabl 3d Plates

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Issue
Journal of Siberian Federal University. Biology. 2016 9 (1)
Authors
Lazarenko, Viktor I.; Shumilova, Anna A.; Proskurin, Yegor V.; Volkov, Vladimir A.; Kirichenko, Andrei K.; Shishatskaya, Ekaterina I.
Contact information
Lazarenko, Viktor I.:V.F. Voino-Yasenetsky Krasnoyarsk State Medical University 1 Partizan Zheleznyak Str., Krasnoyarsk, 660022, Russia; Shumilova, Anna A.:Institute of Biophysics of SB RAS 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia;E-mail: ; Proskurin, Yegor V.:V.F. Voino-Yasenetsky Krasnoyarsk State Medical University 1 Partizan Zheleznyak Str., Krasnoyarsk, 660022, Russia; Volkov, Vladimir A.:V.F. Voino-Yasenetsky Krasnoyarsk State Medical University 1 Partizan Zheleznyak Str., Krasnoyarsk, 660022, Russia; Kirichenko, Andrei K.:V.F. Voino-Yasenetsky Krasnoyarsk State Medical University 1 Partizan Zheleznyak Str., Krasnoyarsk, 660022, Russia; Shishatskaya, Ekaterina I.:Institute of Biophysics of SB RAS 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia
Keywords
maxillofacial surgery; bottom wall of orbit; allocartilage; poly-3-hydroxybutyrate; biocompatibility; biodegradation; osteoprotection
Abstract

The study investigated the resorbable polymeric 3D plates based on polyesters of hydroxybutyric acid – poly-3-hydroxybutyrate (P(3HB)) in comparison with the commercial preparation Ltd. “Plastic” (allocartilage) for regeneration of bottom wall orbit defect of rabbits. The studied 3D plates don’t induce inflammatory reactions after implantation. They can perform function of insulating elements and have osteoprotective properties; they contribute to shortening of the period of injured bone tissue restoration, and complete closure of defect for 60 days

Pages
98-108
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/20185

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