Journal of Siberian Federal University. Humanities & Social Sciences / Special Features of the State of Functional Activity of Neutrophil Granulocytes in Blood During the High Level of Physical Exercises

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Issue
Journal of Siberian Federal University. Humanities & Social Sciences. 2011 4 (9)
Authors
Bazarin, Kirill P.; Savchenko, Andrey A.
Contact information
Bazarin, Kirill P. : Siberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 Russia , e-mail: ; Savchenko, Andrey A. : Siberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 Russia
Keywords
sport; immune system; neutrophil; spontaneous chemiluminescence; induced chemiluminescence
Abstract

In recent years researchers in different countries pay much attention to changes in immune system, which appear as a result of intensified physical exercises. The main reason for such attention lays in the necessity of finding the mechanisms of adaptation to physical loading and a task of corrections of widely spread clinical expressions of immunodeficiency of highly qualified sportsmen, in particular, a high level of susceptibility to infectious diseases. Our work presents results of our comparative research of the functional activity of neutrophil, expressed through a calculated index of activation, for representatives of different sports and the control group, consisting mostly of healthy people, who do not expose to high physical loading. We detected a reliable decrease of the activation index of neutrophils of sportsmen in more than 2 times in comparison to the control group. These results provide grounds for asserting that a high level of physical loading, which is typical of highly qualified sportsmen, has a substantial suppression impact on the immune system, in particular, on the functional activity of neutrophils.

Pages
1251-1259
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/2492

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