Siberian Federal University

Issue

Journal of Siberian Federal University. Biology. 2011 4 (2)

Authors

Salmin, Vladimir V.; Salmina, Alla B.; Fursov, Alexander A.; Frolova, Olga V.; Laletin, Dmitry I.; Fursov, Maxim A.; Yudin, Gennady V.; Malinovskaya, Nataliya A.; Zykova, Larissa D.; Provorov, Alexander S.

Contact information

Salmin, Vladimir V. : Siberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 Russia , e-mail: ; Salmina, Alla B. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Fursov, Alexander A. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Frolova, Olga V. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Laletin, Dmitry I. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Fursov, Maxim A. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Yudin, Gennady V. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Malinovskaya, Nataliya A. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Zykova, Larissa D. : Krasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 Russia; Provorov, Alexander S. : Siberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 Russia

Keywords

optical biopsy; myocardium; ischemia; nitrogen laser

Abstract

Data of experimental assessment of a possibility to use laser-fluorescent analysis of myocardium for detecting alterations caused by ischemia under the conditions of cardiac surgery are presented. It is confirmed that the method of optical biopsy with Nitrogen laser (337 nm) allows registering metabolic changes in myocardium associated with alterations in pyridine nucleotides concentrations, dysfunction of hemoproteids, changes in the activity of NAD(P)H-utilizing enzymes, and development of contraction and death of cardiomyocytes.

Pages

142-157

Paper at repository of SibFU

https://elib.sfu-kras.ru/handle/2311/2560

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).