Journal of Siberian Federal University. Chemistry / Synthesis of Sulfated Arabinogalactan Derivatives with Histidine and Arginine

Full text (.pdf)
Issue
Journal of Siberian Federal University. Chemistry. 2016 9 (3)
Authors
Vasilyeva, Natalia Yu.; Levdansky, Alexander V.; Kazachenko, Alexander S.; Skvortsova, Galina P.; Kuznetsov, Boris N.; Djakovitch, Laurent; Pinel, Catherine
Contact information
Vasilyeva, Natalia Yu.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” 50/24 Akademgorodok, Krasnoyarsk, 660036 Russia; Siberian Federal University; Levdansky, Alexander V.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” 50/24 Akademgorodok, Krasnoyarsk, 660036 Russia; Kazachenko, Alexander S.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” 50/24 Akademgorodok, Krasnoyarsk, 660036 Russia; Skvortsova, Galina P.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” 50/24 Akademgorodok, Krasnoyarsk, 660036 Russia; Kuznetsov, Boris N.: Institute of Chemistry and Chemical Technology SB RAS FRC “Krasnoyarsk Science Center SB RAS” 50/24 Akademgorodok, Krasnoyarsk, 660036 Russia; Siberian Federal University 79 Svobodny, Krasnoyarsk, 660041 Russia; ; Djakovitch, Laurent: IRCELYON 2 Albert Einstein av., F-69626 Villeurbanne Cedex, Lyon, France; Pinel, Catherine: IRCELYON 2 Albert Einstein av., F-69626 Villeurbanne Cedex, Lyon, France
Keywords
sulfated arabinogalactan; histidine; arginine; ion exchange; fixed amino acids; composition
Abstract

For the first time the wather-soluble derivatives of sulfated arabinogalactan with amino acids histidine and arginine were prepared by ion exchange method. The obtained products were studied by elemental analysis and FTIR spectroscopy. From the analysis of FTIR spectra it is concluded that the resulting compounds contain the negatively changed sulfated arabinogalactan as an anion and the protonated forms of histidine and arginine – as a cations. Drugs on the basic of sulfated arabinogalactans with fixed amino acids have prospects for use in medicine

Pages
318-325
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/30717