Siberian Federal University

Issue

Journal of Siberian Federal University. Biology. 2017 10 (2)

Authors

Shidlovskiy, Ivan P.; Shumilova, Anna A.; Shishatskaya, Ekaterina I.

Contact information

Shidlovskiy, Ivan P.: Siberian Federal University 79 Svobodny, Krasnoyarsk, 660041, Russia; Shumilova, Anna A.: Siberian Federal University 79 Svobodny, Krasnoyarsk, 660041, Russia; ; Shishatskaya, Ekaterina I.: Siberian Federal University 79 Svobodny, Krasnoyarsk, 660041, Russia; Institute of Biophysics SB RAS Federal Research Center “Krasnoyarsk Science Center SB RAS” 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia

Keywords

bacterial cellulose; wound dressings; silver nanoparticles; composites; antibacterial activity

Abstract

Bacterial cellulose (BC) is widely used in medicine as a dressing material due to its good biological properties – high biocompatibility, low adhesion and the ability to absorb wound exudate. The BC does not have antimicrobial activity itself, which limits the use of products in infected wounds, and also treatment of wounds in hospitals. A method for producing a two-component composite material based on bacterial cellulose (BC) synthesized in culture of Komagataeibacter xylinus B-12068 with silver nanoparticles [BC/AgNps], by hydrothermal synthesis of AgNO3 in the layer of BC at different temperatures and concentrations of AgNO3, is proposed. The antibacterial activity of BC/AgNps samples against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, and Staphylococcus aureus has been confirmed in vitro with the disc diffusion method. It is shown, that the antibacterial activity of samples is mostly expressed in cultures of P. aeruginosa and S. aureus

Pages

255-264

Paper at repository of SibFU

https://elib.sfu-kras.ru/handle/2311/33375

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).