Journal of Siberian Federal University. Biology: Function of Na/K-pump in Excitable Tissues (Review)

Journal of Siberian Federal University. Biology / Function of Na/K-pump in Excitable Tissues (Review)

Issue: Journal of Siberian Federal University. Biology. 2008 1 (3)
Authors: Boldyrev, Alexander A.
Contact information: Boldyrev, Alexander A. : International Biotechnological Center of Lomonosov Moscow State University, Vorobievy Gory, Moscow, 119991 Russia; aaboldyrev@mail.ru
Keywords: Na/K-ATPase; oligomeric structure; ATP; sodium; potassium; cell signaling
Abstract: Na/K-ATPase is a key enzyme supporting asymmetric distribution of Na and K ions on the outer cell membrane of animal tissues. In the review, current state of Na-pump function is discussed. The data are presented describing molecular properties and location of the enzyme molecule within the cell membrane. Evidence on oligomeric structure of Na/K-ATPase and regulation of the protomers within the complex by ATP are shown. New data illustrating participation of Na/K-pump in cell signaling are presented.
Pages: 206-225
Paper at repository of SibFU: https://elib.sfu-kras.ru/handle/2311/936