Journal of Siberian Federal University. Chemistry / Influence of the Nature of Organic Solvent on Betulin Isolation from an External Layer of a Birch Bark

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Issue
Journal of Siberian Federal University. Chemistry. 2012 5 (3)
Authors
Levdansky, Vladimir A.; Korolkova, Irina V.; Levdansky, Alexandr V.; Ivanchenko, Natalia M.; Kuznetsov, Boris N.
Contact information
Levdansky, Vladimir A.: Institute of Chemistry and Chemical Technology SB RAS; Siberian Federal University , 50-24 Akademgorodok, Krasnoyarsk, 660036 Russia; 79 Svobodny, Krasnoyarsk, 660041 Russia; Korolkova, Irina V.: Institute of Chemistry and Chemical Technology SB RAS , 50-24 Akademgorodok, Krasnoyarsk, 660036 Russia; Levdansky, Alexandr V.: Institute of Chemistry and Chemical Technology SB RAS , 50-24 Akademgorodok, Krasnoyarsk, 660036 Russia; Ivanchenko, Natalia M.: Institute of Chemistry and Chemical Technology SB RAS , 50-24 Akademgorodok, Krasnoyarsk, 660036 Russia; Kuznetsov, Boris N.: Institute of Chemistry and Chemical Technology SB RAS; Siberian Federal University , 50-24 Akademgorodok, Krasnoyarsk, 660036 Russia; 79 Svobodny, Krasnoyarsk, 660041 Russia , e-mail:
Keywords
1; hexane; petroleum-ether; benzene BR-1; cyclohexane; acetonitrile; diethyl ether; ethyl acetate; acetone; isopropanol; ethanol; 1; 4-dioxane; extract; betulin; betulinic acid
Abstract

Extraction of betulin by hexane, petroleum-ether, benzene BR-1, cyclohexane, acetonitrile, diethyl ether, ethyl acetate, acetone, isopropanol, ethanol, and 1,4-dioxane in a Soxhlet’s (extraction) apparatus has been studied. Comparative studying of the obtained extracts has been executed with use of a method of IR-spectroscopy. The content of betulin and betulin acid in extracts, which have been isolated after their concentration to 1/4 initial volumes and in extracts which have been isolated after full removal of solvent, has been defined with using a method of a highly effective liquid chromatography (HPLC). It was established, that use of polar solvents allows to receive extracts with an yield to 28,8 % and the content of betulin from 90 to 95 %.

Pages
302-310
Paper at repository of SibFU
https://elib.sfu-kras.ru/handle/2311/9522