Siberian Federal University

Issue

Journal of Siberian Federal University. Biology. 2012 5 (4)

Authors

Goncharov, Dmitry B.; Nikolaeva, Elena D.; Sukovaty, Alexey G.; Shabanov, Alexandr V.; Shishatskaya, Ekaterina I.; Markelova, Nadezhda M.

Contact information

Goncharov, Dmitry B.: Siberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 Russia; Nikolaeva, Elena D.: Institute of Biophysics SB RAS , 50 Akademgorodok, Krasnoyarsk, 660036 Russia , e-mail: ; Sukovaty, Alexey G.: Institute of Biophysics SB RAS , 50 Akademgorodok, Krasnoyarsk, 660036 Russia; Shabanov, Alexandr V.: Kirensky Institute of Physics SB RAS , 38 Akademgorodok, Krasnoyarsk, 660036 Russia; Shishatskaya, Ekaterina I.: Siberian Federal University; Institute of Biophysics SB RAS , 79 Svobodny, Krasnoyarsk, 660041 Russia; 50 Akademgorodok, Krasnoyarsk, 660036 Russia; Markelova, Nadezhda M.: Krasnoyarsk State Medical University , 1 Partisan Zheleznyak st., Krasnoyarsk, 660022 Russia

Keywords

electrostatic formation; ultrafine fibers; polyhydroxyalkanoates; fibroblasts; cell viability

Abstract

Results of construction and investigation of ultrafine fibers (UFF) made of resorbable poly(3 hydroxybutyrate) by electrostatic formation are presented in this study. Influence of concentration of polymer solutions on fiber diameters and physical-mechanical properties of nonwoven fabric (NF) was investigated. While concentration of polymer solutions increased from 2 to 8 % elongation at break of NF increased from 4,5 to 10,6 % and Young’s modulus decreased from 1,16 to 0,3 GPa. Murine fibroblasts NIH 3T3 were seeded on NF. Using DAPI staining and MTT assay UFF samples were estimated as good cell supporting carriers.

Pages

417-426

Paper at repository of SibFU

https://elib.sfu-kras.ru/handle/2311/9558

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).