Siberian Federal University

In the system, which combines the Fenton reaction or similar (of iron, cobalt, nickel or copper ions with hydrogen peroxide) with the registration of the hydroxyl radical cathodic reduction voltammetric current, the parameters were adjusted for quantitative evaluation of the radical-generating (prooxidant) capacity of metal ions and activity of antioxidants in radical stress induced by metal ions of different nature. Measure of metal ions pro-oxidant activity is the value of the regression coefficient (expressed in plus microAmpere per micromol) of equation for linear approximation, constructed in the coordinates of analytical signal increasing relative to metal ions number in the reaction system. The value of the same regression coefficient (expressed in minus microAmpere per micromol) of equation for linear approximation, constructed in the coordinates of analytical signal decreasing relative to the amount of antioxidant (ascorbic acid) in the reaction system, is a measure of the antioxidant activity of substance